Eastern Sierra
The 150 miles of Highway 395 (also known as the Eastern Sierra Scenic Byway) between Bishop (Inyo County) and Topaz (Mono County) ranks right up there with coastal Highway 1 as California’s most scenic drive. Make sure you take exit 263 to Highway 203 and see very dog-friendly Mammoth Lakes, worth taking a few days to explore. Continue your journey north on Highway 89 to Markleeville (Alpine County) or west on Highway 4 to Bear Valley and you'll add to the lifetime's worth of dog-friendly attractions easily accessible from the San Francisco Bay Area.
You and your four-legged friend will find yourselves surrounded by rugged canyons, granite peaks, rushing streams and vast displays of aspens, cottonwoods and willows that for a few weeks in autumn paint the landscape in yellows, oranges and reds.